In Vivo Assays

The well-characterized duck hepatitis B virus (DHBV) model has been widely used to test the efficacy of chemical disinfectants and non-chemical inactivation processes.
Hepadnavirus Testing, Inc. provides GLP-conforming testing of microbicides, disinfectants, and inactivation systems against DHBV using this duck model. We can directly assay chemical compounds in our facility, or provide high titer DHBV for clients to run through other inactivation processes. Data from these tests are suitable for evaluation by the EPA and FDA.

In Vitro Assays

The EPA has recently ruled (Federal Register 65:166, August 25, 2000) that in vitro assays using duck hepatitis B virus (DHBV) as a surrogate for human hepatitis B virus (HBV) are "appropriate and preferred" methods to evaluate the efficacy of disinfectants that claim to be active against HBV.

Hepadnavirus Testing, Inc. provides GLP-conforming in vitro laboratory testing of microbicides, disinfectants, and inactivation systems against DHBV. The testing method follows the EPA-approved protocol that outlines the experimental design and the statistical criteria for a valid and acceptable result.

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